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Using transpancreatic sphincterotomy () in difficult cannulation cases was useful to achieve successful cannulation with an acceptable PEP rate and less frequent post-ERCP bleeding and perforation compared to needle-knife precut (NKP. SciReports #ERCP
MA: Patients treated with olanzapine, risperidone, and quetiapine were more likely to report weight gain and experience clinically significant (≥%) weight gain vs. those treated with placebo with their off-label use (MD-OLZ = 3.24 kg; 2.5–3.90)
I was curious if phytoplankton used similar mechanisms; turns out DIATOMS also use calcium ions to communicate across entire populations coordinating mass events like blooming! 🦠➡️🦠 ⬇️ 🦠 Here's a pic of calcium wave moving thru a diatom cell! (3/3)
Online NOW | Nature Methods Visualizing the native cellular organization by coupling cryofixation with expansion microscopy () Its simplicity will contribute to its widespread use in super-resolution #Microscopy. naturemethods isciverse
"I now use the word "#weaving" instead of "" to describe the process of combining Māori knowledge and science. When something is weaved together, the integrity of the components is untouched but the whole is ultimately stronger." #organization
A speech planning network for interactive language use Uses intracranial EEG to precisely measure neural activity as participants perform interactive tasks >they '' a planning network used when preparing speech actions & cf with natural conversation
#avct Also research use of Affimer tech in identification of drugglable hotspots on the so-called '' cancer protein, RAS! RAS mutations responsible for ‘25-30% of all known cancers’ so their targeting is an integral step in fight against cancer
KozolRobert et al. use zebrafish models to investigate sensorimotor deficits linked to dysfunction in Phelan-McDermid Syndrome. Dallmanlab Phelan_McDermid PhelanMcDermid McdermidPhelan ZebrafishRock UMBGSO NICHD_NIH SFARIorg NewsAtTheU
hutcho66 JStabbington Captainturtle No. Fomites do still spread, always have. The point was, the exposure is from aerosolized spread. So greater effort needs to be made with masking/ventilation. It was never one OR the other, it was about portioning our focus on the greater threat.
Engineered HaloTag variants for fluorescence lifetime multiplexing Nature Methods, Published online: 16 December 2021; doi:10.1038/s41592-021-01341-x HaloTag variants offer distinct brightness and fluorescence lifetimes compared with when labe…
Well this is exciting!! #anakinra EMA approved for #COVID19 #suPAR guided. Enter stage-left! 🥁 Based on the #savemore trial in NatureMedicine dfmcauley agordonICU PeterHorby LCalabreseDO How are we going to test for #suPAR?
Interesting - DavidGoertsen VivianGradinaru & Caltech colleagues (+) report AAV capsid variants with brain-wide transgene expression & decreased liver targeting after intravenous delivery in both mouse & marmoset; AAV.CAP-B10 & AAV.CAP-B22
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