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"[The] () inflammasome is a key inflammasome expressed by microglia [2], and is activated by multiple protein aggregates associated with neurodegenerative disease..."
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lipo_fan Thanks for the reference. This article is also relevant Quantifying on HDL with nanoparticle-gated electrokinetic membrane sensor for accurate cardiovascular risk assessment
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Lowering interferon without interfering with #CART () Could a toci/emapalumab tango improve outcomes for pts? 💃 #bmtsm #lymsm
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RT SikkemaLisa: Today our Human Lung Cell Atlas () paper came out in Nature Medicine ! The includes 2.4M c…
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Our deep learning-based model showed improved predictive performance of lymph node metastasis 🔗 suggesting that with further refinement and validation, it could be useful in informing clinical decision making. Read the study, published in nature: (1/2)
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Recent paper by Habets et al. says "Annotation was performed with RASTtk on the server followed by a manual curation using BLASTp and HHPred and visualization with Easyfig."
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2) Source "Three genes containing non-synonymous protein-coding changes associated with severe disease were also found to have significant effects from differential gene expression SLC22A31, and TKY2"
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sm9eb MichaelESmith Wadi Feynan 16 is a PPNA site in Jordan with a large communal structure () within the settlement.
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Am reading the new paper by yi_ding_ et al. from bpasaniuc lab. An interesting read on polygenic risk scores & their (non)transferability across populations. Given the hype around PRS and their (!) use for embryo selection this Fig. is terrifying.
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Deadly mushroom poison might now have an antidote. The mushroom toxin could not enter cells that lacked a functional version of involved in N-glycosylation - Wow, how that be !!!
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🚨 New article 🚨 "There is a growing emphasis worldwide on the use of knowledge mobilization () to improve policies and practices with the latest research evidence", Hamid Golhasany & Blane Harvey #UsingEvidenceBetter
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Polarizing pyruvate, lactate and simultaneously for multiplexed #hyperpolarized #MRI experiments or improving the throughput of your #dDNP: our last SciReports paper with Thanh Phong Lê and AndreaCapozzi5 powered by snf_ch and CIBM_ch #NMRChat
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#Nature A radio-detected type Ia supernova with helium-rich circumstellar material SN showing helium-rich circumstellar material, infrared emission and, for the first time in a SN Ia to our knowledge, a radio counterpart. cc pcoffeebreak
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Did you know that the data from our first #OpenScope project with the AllenInstitute on predictive learning in cortex is available on-line! Now, you can find the () paper describing the dataset and linking to all the data/code at ScientificData:
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We offer an individual-level interpretation of polygenic score () transferability across genetic ancestries: accuracy varies individual-to-individual across the genetic-ancestry continuum, even in populations usually labeled as homogeneous. 1/
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#42 #bestreads NJoshiBWH et al reported triglycerol monostearate () from the #FDA #GRAS pool, generating gels, harnessing arthritis severity dictated drug release for triamcinolone acetonide (by degradation with MMPs’ increase in synovial fluid)
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Inhibiting membrane rupture with antibodies limits tissue injury
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New paper from the Maguire lab WCHN_UCL asking if hippocampal subfield volumes are associated with autobiographical memory retrieval ability… The full length of 402 hippocampi were ** segmented to bring you an answer! Find out here:
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BreakingNewsFi2 KellyGoodmanPhD Censored4sure zianiniSLO Congressizazzho PhilipRafferty5 Yep, I can see the size of the '' with your line of questioning. Meanwhile, science and medicine just get on with their research.
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tcastandrew JunkScience We evolved during the Pleistocene, but human civilisation & permanent agriculture only started about 10,000 years ago when the climate was fairly stable with CO2 levels around and global mean surface temperature was about 1.2C less than now.
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Deadly mushroom poison might now have an antidote — with help from
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13f) refs. more evidence for Hunter-farmer hypothesis- people with '' traits in small-s…
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Starchild737 Fly_Sistah DNA studies alone is sufficient in busting this afrocentrist myth. I fail to understand why you regurgitate these absurd ideas to begin with given that the even the "" people (Nilo-Saharan & Cushites) in that region has no ties to modern AA
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Interesting findings from an international collaboration led by Cambridge_Uni indicates that problems with the brain's ability to '' itself of unnecessary connections may underlie a wide range of mental health disorders that begin during adolescence
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lisajdubreuil Also, Ozempic is not the only glp-1 drug where 2 year sustained weight loss is see. Liraglutide which is weaker version, showed same in 2011. If you apply your own "" logic, the is towards sustained weightloss with therapy continuation.
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I am sure the I am the idiot that is missing the plot, but seems to me the main point of their "" theory was already expressed by kjmbishop and me 8 years ago in a quite visible venue ( ). Information content has nothing to do with "aliveness".
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GWAS of impulsive personality traits and drug experimentation, with a nice functional follow-up locus in mice by Sanchez-Roige et al. "Porcupine plot" Is it what we're calling it now ðŸ˜AbePalmer ?
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Vaccinated individuals with severe obesity (BMI > 40 kg/m2) were 76% more likely to experience hospitalization or death from COVID-19
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“These may explain how SARS-CoV-2 effectively replicates in asymptomatic individuals without cuasing respiratory dysfunction, and indicate a risk of enhanced coinfection with other viruses.†💥 💥💥💥💥💥
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First author Jason Luke, MD, and colleagues evaluated if epigenetic therapy plus inhibition and immune checkpoint blockade has clinical benefit. Although the it was well-tolerated, it was not associated with substantial clinical response in patients.