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DoctorZen 5/7 But let’s assume you are 100% correct and that more is needed than even electron microscopy. What about techniques like and which show that immunolabeling can be combined with ultrastructural mapping of connectivity?
Exciting study showing KRAS specificity of is due to its binding to H95 of KRAS as we showed with DARPins in 2019. Converting this compound as a degrader might increase its efficacy!
Many thanks to co-authors and colleagues for contributions and conversations (heyrims rrockne and more off Twitter, COHMathOnc cofcssm).
Work is currently posted on bioRxiv ( ) and data and code is available on GitHub ( ). (12/12)
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